Antitumor Studies of Earthworm Fibrinolytic Enzyme Component A from Eisenia foetida on Breast Cancer Cell Line MCF-7
نویسنده
چکیده
Earthworm is widely used in Chinese traditional medicine. Previous studies on earthworm extracts have demonstrated its ability to improve haemostatic disorders[5] and stimulate wound healing[6]. In addition, higher concentrations of earthworm extracts are nontoxic and have excellent antiinflammatory and antipyretic properties[7]. Further researches have revealed the potential for using earthworm extracts as antibacterial[8], antifungal[9], antiviral[10] and antitumor[8,9] agents. In this study, earthworms were studied to determine their active components used in the traditional prescriptions as starting materials.
منابع مشابه
Molecular cloning and characterization of cDNA encoding fibrinolytic enzyme-3 from earthworm Eisenia foetida.
The earthworm fibrinolytic enzyme-3 (EFE-3, GenBank accession No: AY438622), from the earthworm Eisenia foetida, is a component of earthworm fibrinolytic enzymes. In this study, cDNA encoding the EFE-3 was cloned by RT-PCR. The cDNA contained an open reading frame of 741 nucleotides, which encoded a deduced protein of 247 amino acid residues, including signal sequences. EFE-3 showed a high degr...
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